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    The thiazolidinediones /?a?.??zo?l?di?n?da?.o?n/, also known as glitazones, are a class of medications used in the treatment of diabetes mellitus type 2. They were introduced in the late 1990s. They contain a functional group in which thiazolidine serves as a dione.ACTOS is a thiazolidinedione that depends on the presence of insulin for its mechanism of action. ACTOS decreases insulin resistance in the periphery and in the liver resulting in increased insulin-dependent glucose disposal and decreased hepatic glucose output. Pioglitazone is not an insulin secretagogue.
    Most drugs for diabetes, including Actos and its sister drug Avandia, cause weight gain. … So Actos and Avandia can cause weight gain, because insulin is now working efficiently and the excess will be stored as fat.
    Less serious side effects may include:**cold symptoms such as stuffy nose, sneezing, cough, sore throat;**headache;**gradual weight gain;**muscle pain;**back pain; or.**tooth problems.
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    The name of your medicine is Pioglitazone 15mg, 30mg or 45mg Tablets (referred to as pioglitazone throughout this leaflet). Pioglitazone is an anti-diabetic medicine used to treat type 2 (non-insulin dependent) diabetes mellitus when metformln is not suitable or has failed to work adequately.
    Glucotrol (glipizide) is an oral diabetes medicine that helps control blood sugar levels by helping your pancreas produce insulin. Glucotrol is used together with diet and exercise to treat type 2 diabetes.
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